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Clinical Science

Evidence-Based<br />Longevity Methods

Explore the advanced diagnostics, cellular therapies, circadian nutrition protocols, and movement modalities we utilize to target the hallmarks of aging and optimize biological performance.

Clinical Science
Epigenetic DNA Age Testing
Diagnostics

Epigenetic DNA Age Testing

Evaluate biological age speed by analyzing DNA methylation patterns

Epigenetic screening analyzes chemical modifications (methylation) at specific sites across your genome. This provides an accurate biological clock reading, showing whether your body is aging faster or slower than your chronological baseline and highlighting biological levers for reversal.

Key Biological Benefits:

  • check_circleAccurate biological age mapping
  • check_circleTracks cellular aging speed over time
  • check_circleReveals healthspan intervention effectiveness
menu_bookPublished in Cell Stem Cell (Horvath Clock, 2013)
VO2 Max Cardiovascular Mapping
Diagnostics

VO2 Max Cardiovascular Mapping

Assess cardiopulmonary fitness and metabolic peak output under physical stress

Using advanced metabolic cart screening during a progressive maximal exercise test, we measure your peak oxygen consumption (VO2 Max) and anaerobic thresholds. This represents the ultimate diagnostic marker of biological youth and cardiovascular longevity.

Key Biological Benefits:

  • check_circleMeasures cardiorespiratory capacity
  • check_circleDetermines cellular aerobic efficiency
  • check_circlePinpoints custom heart-rate training zones
menu_bookAssociated with 5x reduction in all-cause mortality (JAMA, 2018)
Chronotype-Aligned Dining
Nutrition

Chronotype-Aligned Dining

Match nutrient timing with your biological clock to optimize metabolic health

Our dietary team crafts custom anti-inflammatory meal protocols synchronized with your circadian rhythm (chronotype). Aligning carbohydrate and protein intake with diurnal cortisol and melatonin curves stabilizes insulin sensitivity and improves sleep recovery.

Key Biological Benefits:

  • check_circleStabilizes blood glucose & insulin curves
  • check_circleOptimizes circadian digestive enzymes
  • check_circleImproves nighttime sleep cycles & HRV
menu_bookSalk Institute Circadian Biology Research (Panda et al.)
Active Vagus Nerve Stimulation
Therapies

Active Vagus Nerve Stimulation

Tone your parasympathetic nervous system to resolve chronic stress response

Using micro-current electrical stimulation targeting the auricular branch of the vagus nerve, we trigger parasympathetic down-regulation. This directly lowers resting heart rate, reduces cortisol output, and increases heart rate variability (HRV).

Key Biological Benefits:

  • check_circleResolves chronic sympathetic fight-or-flight states
  • check_circleDramatically improves heart rate variability
  • check_circleAccelerates physical and cognitive recovery
menu_bookFDA cleared for nervous system regulation and anti-inflammatory pathways
Hyperbaric Oxygen Chambers (HBOT)
Therapies

Hyperbaric Oxygen Chambers (HBOT)

Saturate blood plasma with pure oxygen to stimulate stem cell release

Under increased atmospheric pressure (1.5 to 2.0 ATA), inhaling 100% pure oxygen dissolves up to 15 times more oxygen directly into blood plasma and cerebrospinal fluid. This hyper-oxygenation triggers angiogenesis, stimulates cellular healing, and drives endogenous stem cell release.

Key Biological Benefits:

  • check_circleTriggers tissue healing and angiogenesis
  • check_circleStimulates stem cell release
  • check_circleReduces systemic biomarkers of inflammation
menu_bookShown to reverse markers of cellular aging (Aging Journal, 2020)
NAD+ Cellular Infusion Therapy
Therapies

NAD+ Cellular Infusion Therapy

Replenish intracellular NAD+ levels to restore DNA repair and energy production

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme crucial for cellular ATP generation and sirtuin activity. Direct intravenous infusion bypasses digestive degradation, replenishing systemic levels to repair DNA damage, improve cognitive function, and enhance mitochondrial performance.

Key Biological Benefits:

  • check_circleSupports mitochondrial energy generation
  • check_circleActivates sirtuin anti-aging enzymes
  • check_circlePromotes cellular DNA repair mechanisms
menu_bookScientific baseline in Harvard longevity research (Sinclair et al.)
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